Why do arthritis symptoms get worse at night?

According to experts, there are many causes that lead to joint pain or worsening late at night and early in the morning.

One of them is associated with changes in the level of hormones and cytokines, which are proteins that transmit cellular signals in the body.

Researchers hypothesize that, it is also possible that due to arthritis medications that people with arthralgia use during the day, by evening the effect may cease to lead to an outbreak of pain.

In addition, the circadian rhythm of the body plays a decisive role in pain.

Specifically, in people with rheumatoid arthritis, the body secretes less of the anti-inflammatory chemical cortisol at night, which increases the pain associated with inflammation.

Other processes can also increase rheumatoid arthritis pain, including the release of pro-inflammatory cytokines at night, an increase in the number of cells moving to the inflamed tissue, and changes in the body’s immune response.

Besides, the body secretes higher amounts of melatonin and prolactin at night, which also causes an increase in inflammatory cytokines.

A person’s arthritis inflammation and pain can get worse if the joint pain begins before they go to bed.

Too hard, uncomfortable mattresses or pillows put pressure on the joints and irritate arthritis.

People with joint pain who have other risk factors for insomnia, such as high levels of stress or taking caffeine before bedtime may also experience joint pain at night.

Numerous studies show a link between arthritis and lack of sleep. People with arthritis may have difficulty falling asleep and not sleeping deeply, the quality of sleep is lower due to joint pain.

Since insomnia can make the pain worse at night, the person with arthritis needs to improve sleep as a treatment for pain.

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